Melatonin
Common Names: N-Acetyl-5-methoxytryptamine, It, In
Psychoactive Effects
Positive Effects
- Euphoria
- Energy
Neutral Effects
- Sedation
- Relaxation
- Reduced anxiety
- Pupil constriction
- Drowsiness
- Reduced body temperature
Negative Effects
- Anxiety
Dosage Guidelines
| Route | Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|---|
| Oral | 0.5-1 mg | 1-3 mg | 3-5 mg | 5-10 mg | 10+ mg |
Duration
| Phase | Duration |
|---|---|
| Onset | 30-60 minutes |
| Peak | 1-2 hours |
| Total | 4-6 hours |
| After effects | 6-8 hours |
Pharmacology
Mechanism of Action: Dopamine receptor modulator
Risks and Harm Reduction
AddictionDependenceToxicity
⚠️ Important: Always practice harm reduction. Start with low doses, test your substances, and ensure a safe set and setting. Never use alone.
Legal Status
Legal
Disclaimer: Legal status varies by jurisdiction and may change. This information is for educational purposes only.
References
- • Reiter, R. J., et al. (2016). Melatonin as an antioxidant: under promises but over delivers. Journal of Pineal Research, 61(3), 253-278.
- • Zisapel, N. (2018). New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation. British Journal of Pharmacology, 175(16), 3190-3199.
- • Information compiled from PsychonautWiki